Berberine is a naturally occurring compound found in plants like barberry, goldenseal, and Oregon grape. It has been used in Traditional Chinese Medicine for centuries and is now the subject of impressive modern clinical research.
Berberine activates AMPK (AMP-activated protein kinase) — an enzyme that acts as a cellular energy sensor. AMPK activation increases glucose uptake in cells, reduces liver glucose production, and enhances fat burning.
A landmark 2008 study in Metabolism journal found berberine as effective as metformin for controlling blood sugar in type 2 diabetics. This finding has generated significant clinical interest.
Since both berberine and keto reduce blood glucose and insulin through overlapping mechanisms, combining them may offer synergistic benefits. However, people on diabetes medication should consult their GP before adding berberine.
Standard dose: 500mg three times daily with meals. Side effects are mainly gastrointestinal (start low). Not safe in pregnancy.
Pair berberine supplementation with blood-sugar-stable keto meals from our keto main dish collection and keto beverages.